"Severe pneumonia with co-infection of H5N1 and SARS-CoV-2: a case report"
Case presentation:
"A 52-year-old woman presented with a fever, which has persisted for the past eight days, along with worsening shortness of breath and decreased blood pressure. Computed tomography (CT) revealed an air bronchogram, lung consolidation, and bilateral pleural effusion. The subsequent polymerase chain reaction (PCR) of the bronchoalveolar lavage fluid (BALF) revealed positivity for H5N1 and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)."
Conclusion:
"The H5N1 influenza virus is a cause of severe pneumonia. The clinical presentation of the patient had a predomination of H5N1 influenza rather than COVID-19. A PCR analysis for the identification of the virus is necessary to reveal the pathogen causing the severe pneumonia. The patient exhibited an excellent prognosis upon the use of the appropriate antiviral medicine."
"Since 9 of 15 of the affected dairy herds in Michigan were closed herds which did not bring any new cattle into the herd, restriction of live cattle movements would not have prevented disease in these herds."
Good point and that is why the CDC testing people is so important.
"HPAI disease spread between dairy and poultry premises can be mitigated by identifying potential interconnections between operations (people, conveyances, etc.) and increasing biosecurity practices on all premises and associated animal businesses (e.g., milk haulers, deadstock /contract haulers and other shared vehicles/trailers between premises,
livestock markets). Identifying as many affected herds as possible will assist in assessing the scope of the event and allow decision-makers to better manage the response." "100% of affected dairy premises have regular visits by veterinarians, nutritionist/feed consultant,
and/or contract haulers (e.g., cattle or manure); the majority of these visitors have direct contact with cattle."
The mice have been in New Mexico and they aren't being shipped around like cows and don't have as much contact with people. Containing the cow outbreaks would significantly reduce the risk of human infection thus buying us more time. It's not a guarantee but it mitigates the risk.
"Severe pneumonia with co-infection of H5N1 and SARS-CoV-2: a case report"
Case presentation:
"A 52-year-old woman presented with a fever, which has persisted for the past eight days, along with worsening shortness of breath and decreased blood pressure. Computed tomography (CT) revealed an air bronchogram, lung consolidation, and bilateral pleural effusion. The subsequent polymerase chain reaction (PCR) of the bronchoalveolar lavage fluid (BALF) revealed positivity for H5N1 and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)."
Conclusion:
"The H5N1 influenza virus is a cause of severe pneumonia. The clinical presentation of the patient had a predomination of H5N1 influenza rather than COVID-19. A PCR analysis for the identification of the virus is necessary to reveal the pathogen causing the severe pneumonia. The patient exhibited an excellent prognosis upon the use of the appropriate antiviral medicine."
https://link.springer.com/article/10.1186/s12879-023-08901-w
"Since 9 of 15 of the affected dairy herds in Michigan were closed herds which did not bring any new cattle into the herd, restriction of live cattle movements would not have prevented disease in these herds."
https://www.aphis.usda.gov/sites/default/files/hpai-h5n1-dairy-cattle-mi-epi-invest.pdf
Good point and that is why the CDC testing people is so important.
"HPAI disease spread between dairy and poultry premises can be mitigated by identifying potential interconnections between operations (people, conveyances, etc.) and increasing biosecurity practices on all premises and associated animal businesses (e.g., milk haulers, deadstock /contract haulers and other shared vehicles/trailers between premises,
livestock markets). Identifying as many affected herds as possible will assist in assessing the scope of the event and allow decision-makers to better manage the response." "100% of affected dairy premises have regular visits by veterinarians, nutritionist/feed consultant,
and/or contract haulers (e.g., cattle or manure); the majority of these visitors have direct contact with cattle."
"It is difficult to get a man to understand something, when his salary depends on him not understanding it"
---Upton Sinclair
Likely too late for containment now. Follow the mice...
The mice have been in New Mexico and they aren't being shipped around like cows and don't have as much contact with people. Containing the cow outbreaks would significantly reduce the risk of human infection thus buying us more time. It's not a guarantee but it mitigates the risk.