13 Comments
founding
Feb 25Liked by TACT

TACT...Nice photograph at the top. If that photograph doesn't scream 'FRESH AIR' , I don't know what does.

I enjoyed your quixotic hope in reference to the Center for Disease Circulation ("How many were vaccinated? Hopefully, they make this distinction clearer in updates.")

Don't hold your breath, TACT.

Regarding the JN.1 quasispecies swarm, see the last line in this reference.

There is something different about the JN.1 swarm, perhaps in the enzymes it is using to potentiate infection that have not yet been completely elucidated.

https://www.biorxiv.org/content/10.1101/2024.02.14.579654v1

Lastly, while you mentioned measles (which is definitely a problem), don't sleep on DENGUE.

To the folks in Florida and Texas, all I can say is "SUMMER IS COMING"

Thanks for your tireless work.

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Fascinating. If not, slightly depressing update, but forewarned is forearmed. I’m particularly interested in the study on Paxlovid. As a lay person I’m making my way through it and having trouble understanding if they adequately accounted for all confounding variables. I see it mentioned BMI is a significant piece of missing data. age might be another. I thought I saw a vague reference to including that in the demographics, but wasn’t 100% clear. On a surface level, it seems hard to understand that a drug that dramatically and quickly reduces viral load in your body couldn’t be at least somewhat helpful for long-term downstream effects. The study didn’t look at what we now know are some of the most common long Covid symptoms as well, such as cognitive impairment/brain, fog, exercise, intolerance and PEM. Would love for people more experienced than I am in reading through study methodology to comment on how solid the conclusions of the study might be.

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founding
Mar 2Liked by TACT

Don't know if the Center for Disease Circulation (CDC) has provided any information on measles breakthrough infections, but I did see one such case reported on Xitter from a parent of a fully vaccinated child in the Florida cohort. Fortunately, this case appears to have resolved quickly.

A little light reading before bedtime...

https://pubmed.ncbi.nlm.nih.gov/36013985/

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Feb 28Liked by TACT

My spouse is one of 7 and he has 50 first cousins…the eldest cousin is 75. He has pulmonary fibrosis and in the hospital. His family doesn’t know why he has pulmonary fibrosis. 🤦🏾‍♀️

I could respond and say ..Duh…it’s called covid19 aka saracov2 - but they won’t believe me…

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founding
Feb 27Liked by TACT

Well, well, well...it looks like it is NOT just ACE2.

We're not in Kansas, anymore...

https://www.pnas.org/doi/full/10.1073/pnas.2317026121

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Feb 26Liked by TACT

So I’m hoping it’s still safe to consider myself immune after having had measles decades ago?

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