The paper referenced that compares HIV-1 to SARS2 states that a SARS2 infection is cleared. I think that's not true. There's persistence until proven otherwise IMHO. There have been many autopsies that showed viable virus in supposedly negative patients. Comments?
There is no doubt that COVID persists in as many places as it can throughout the body. The pancreas, kidneys, lungs, brain, CNS, testicles, breast, gastrointestinal tract, and likely anywhere outside the reach of T-cells.
1. Viral presence in the lung up to 359 days after the acute phase of disease, including in patients with negative nasopharyngeal swab tests. The lung of PC patients are characterized by the accumulation of senescent alveolar type 2 cells.
8. "Effect of COVID-19 on Male Reproductive System – A Systematic Review"
"The impaired semen quality may be related to fever and inflammation. Pathological analysis of the testis/epididymis showed that SARS-CoV-2 viral particles were positive in 10 testicular samples, and the spermatogenic function of the testis was impaired."
9. "Here, we established the presence of residual virus within the appendix, skin, and breast tissue of 2 patients who exhibited LC symptoms, 163 to 426 days upon symptom onset."
"Our positive finding in the breast tissue also corroborated with recent reports that immunocompromised patients had also experienced LC symptoms and persistent viral replication. Overall, our findings, along with emerging LC studies, raises the possibility of the gastrointestinal tract functioning as a reservoir."
Thank you! I tell people that sarscov2 is like having hiv. So many people are getting cancer…. And they die quickly.
I also say that sarscov2 is like Ebola on the inside…it’s a disease of our blood…
The paper referenced that compares HIV-1 to SARS2 states that a SARS2 infection is cleared. I think that's not true. There's persistence until proven otherwise IMHO. There have been many autopsies that showed viable virus in supposedly negative patients. Comments?
There is no doubt that COVID persists in as many places as it can throughout the body. The pancreas, kidneys, lungs, brain, CNS, testicles, breast, gastrointestinal tract, and likely anywhere outside the reach of T-cells.
1. Viral presence in the lung up to 359 days after the acute phase of disease, including in patients with negative nasopharyngeal swab tests. The lung of PC patients are characterized by the accumulation of senescent alveolar type 2 cells.
https://www.medrxiv.org/content/10.1101/2022.11.28.22282811v1
2. "We were able to detect the virus in the oesophagus, large intestine, kidney, placenta, lung, & brain."
assets.researchsquare.com/files/rs-14418
3. “Tonsils and adenoids are important sites of SARS-CoV-2 infection in asymptomatic children.”
Persistent infections uncovered through genetic analysis
A 55% increase in the likelihood of reporting Long COVID more than 12 weeks after infection if they had persistent infections.
https://www.medrxiv.org/content/10.1101/2023.01.29.23285160v1
4. Asymptomatic yet persistent infection in children's tonsils⬅️ suggest that lymphoid tissue may play an important role in community transmission.
➡️ CD123+dendritic cells were most infected cells followed by CD14+ monocytes, CD4 & CD8 T-cells. ⬅️
https://www.sciencedirect.com/science/article/pii/S1808869422001392
5. "SARS-CoV-2 infection and persistence throughout the human body and brain"
"Our data prove that SARS-CoV-2 causes systemic infection and can persist in the body for months."
https://www.nature.com/articles/s41586-022-05542-y
6.SARS-CoV-2 is associated with changes in brain structure in UK Biobank
"a degenerative spread of the disease through olfactory pathways, of neuroinflammatory events, or of the loss of sensory input"
"a more pronounced loss of grey matter in crus II, part of the cognitive and olfactory-related lobule VII of the cerebellum"
https://www.nature.com/articles/s41586-022-04569-5?feature%5Bconsent-app%5D=1&optanonConsent=15
7. "Semen Proteomics of COVID-19 Convalescent Men Reveals Disruption of Key Biological Pathways Relevant to Male Reproductive Function"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928495/
8. "Effect of COVID-19 on Male Reproductive System – A Systematic Review"
"The impaired semen quality may be related to fever and inflammation. Pathological analysis of the testis/epididymis showed that SARS-CoV-2 viral particles were positive in 10 testicular samples, and the spermatogenic function of the testis was impaired."
https://www.frontiersin.org/articles/10.3389/fendo.2021.677701/full
9. "Here, we established the presence of residual virus within the appendix, skin, and breast tissue of 2 patients who exhibited LC symptoms, 163 to 426 days upon symptom onset."
"Our positive finding in the breast tissue also corroborated with recent reports that immunocompromised patients had also experienced LC symptoms and persistent viral replication. Overall, our findings, along with emerging LC studies, raises the possibility of the gastrointestinal tract functioning as a reservoir."
https://www.frontiersin.org/articles/10.3389/fimmu.2022.939989/full?trk=public_post_comment-text
Is there any hope to preventing replication like with HIV antivirals, or at least slowing it down?