Ivermectin
Studies show Ivermectin is not effective against COVID and may actually cause harm.
1. "Inappropriate use of ivermectin during the COVID-19 pandemic: primum non nocere!"
In case you don't know what it means,
➡️ "First, Do NO harm"⬅️
https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(22)00161-6/fulltext
2. Toxic Effects from Ivermectin Use Associated with Prevention and Treatment of Covid-19
"These cases illustrate the potential toxic effects of ivermectin, including severe episodes of confusion, ataxia, seizures, and hypotension, and the increasing frequency of inappropriate use. There is insufficient evidence to support the use of ivermectin to treat or prevent Covid-19,3 and improper use, as well as the possible occurrence of medication interactions,5 may result in serious side effects requiring hospitalization."
https://www.nejm.org/doi/full/10.1056/NEJMc2114907
3. Findings In this open-label randomized clinical trial of high-risk patients with COVID-19 in Malaysia, a 5-day course of oral ivermectin administered during the first week of illness did not reduce the risk of developing severe disease compared with standard of care alone.
Meaning The study findings do not support the use of ivermectin for patients with COVID-19.
4. "Compared with the standard of care or placebo, IVM did not reduce all-cause mortality, LOS, or viral clearance in RCTs in patients with mostly mild COVID-19. IVM did not have an effect on AEs or SAEs and is not a viable option to treat patients with COVID-19."
https://academic.oup.com/cid/article/74/6/1022/6310839
5. Randomized trial of metformin, ivermectin, and fluvoxamine for Covid-19
"None of the three medications that were evaluated prevented the occurrence of hypoxemia, an emergency department visit, hospitalization, or death associated with Covid-19."
https://www.nejm.org/doi/full/10.1056/NEJMoa2201662
6. ""Double-blind, randomized, placebo-controlled, trial involving symptomatic, positive adults from 12 public health clinics in Brazil"
"Treatment w/ivermectin did NOT result in a lower incidence of medical admission to a hospital due to progression of Covid"
https://www.nejm.org/doi/full/10.1056/nejmoa2115869
7.Ivermectin compared with placebo in Mexican patients with asymptomatic
& mild COVID: a randomized clinical trial
"Ivermectin is not effective in the progression to severe state & reducing symptoms in adults with asymptomatic & mild COVID."
https://www.researchsquare.com/article/rs-1640339/latest.pdf
8. "Ivermectin as a potential treatment for mild to moderate COVID-19–a double blind randomized placebo-controlled trial"
Conclusion
"There was no difference in the primary outcome i.e. negative RT-PCR status on day 6 of admission with the use of ivermectin." Severe cases not included.
https://www.medrxiv.org/content/10.1101/2021.01.05.21249310v1
9. Do not use drug designed to treat parasitic worms for COVID-19
Oregon Poison Center at OHSU experiences substantial increase in calls involving intentional misuse of ivermectin
https://news.ohsu.edu/2021/08/24/do-not-use-drug-designed-to-treat-parasitic-worms-for-covid-19
10: Published: Feb 2023
Double-blind, randomized, placebo-controlled platform trial during Feb to Jul 2022, the median time to recovery was 11 days in the ivermectin group and in the placebo group.
These findings do not support the use of ivermectin.
https://jamanetwork.com/journals/jama/fullarticle/2801827
FDA: Why You Should Not Use Ivermectin to Treat or Prevent COVID-19
“The FDA has not authorized or approved ivermectin for use in preventing or treating COVID-19 in humans or animals. Ivermectin is approved for human use to treat infections caused by some parasitic worms and head lice and skin conditions like rosacea.”
“Currently available data do not show ivermectin is effective against COVID-19. Clinical trials assessing ivermectin tablets for the prevention or treatment of COVID-19 in people are ongoing.”
https://www.fda.gov/consumers/consumer-updates/why-you-should-not-use-ivermectin-treat-or-prevent-covid-19